01
Is medication included?
A $149 medication price can become a $188 first-month total when a required membership is billed separately.
U.S. cash-pay comparison · Updated August 28, 2026
The lowest starting GLP-1 price in our comparison.
SurpassMD starts at $114 per month for semaglutide, lower than every other provider displayed here. Compare medication cost, required fees, commitments, and what is actually included.
Starting promotional price for eligible patients. Medication, dose, and clinician approval affect actual price.
Displayed starting totals
*Different medication types and terms. Read the table before comparing.
Lowest advertised start in this table10 provider-owned sourcesRequired fees separatedCompounded vs. brand identified
The comparison
Start with the total, then inspect the terms.
A low number can be accurate and still be incomplete. We show the pricing basis next to every starting figure.
Use this table as a shopping shortlist. Verify your exact price, state availability, medication format, dose, cancellation terms, and clinical eligibility on the provider’s site before paying.
| Provider | Lowest visible total | Semaglutide | Tirzepatide | What the price means | Next step |
|---|---|---|---|---|---|
SurpassMDLowest Compounded injections |
$114/mo Starting promotional price; medication and dose affect price |
$114/mo | $177/mo | Medication, clinician review, fulfillment and cold-chain shipping Recurring subscription; cancel anytime |
Check eligibility |
MEDVi Compounded injections |
$116 first month Landing page contains both sale and full-price figures |
$116 start; $166 ongoing | $166 start; $199 ongoing | Medication, physician review, care plan, guidance and shipping Promotional first month; displayed ongoing price lock |
View provider |
Fridays Compounded injections |
$150/mo $249 semaglutide or $359 tirzepatide month-to-month |
$150/mo | $240/mo | Medication and program services Discounted price uses prepaid multi-month billing |
View provider |
DirectGLP Compounded injections |
$166/mo Bundled starting price; no separate membership fee |
$166/mo | $199/mo | Provider review, medication, shipping and support Displayed price is based on a 3-month plan |
View provider |
Found Compounded injections |
$169/mo $169 monthly equivalent prepaid for 12 months; $289 month-to-month |
GLP-1 from $169/mo | Varies by plan | Cash-pay GLP-1 treatment program Lowest rate requires a 12-month prepaid plan |
View provider |
Ro FDA-approved brand options |
$188 first month $149 medication plus $39 first-month membership; ongoing membership from $74 |
$149 pill / $199 pen | $299 pen | Medication plus a separate Body membership Lowest $74 membership rate is prepaid annually |
View provider |
Hims & Hers FDA-approved brand options |
$188 first month Ongoing total begins around $298 if medication stays $149 |
Medication from $149 | Varies by option | Medication plus separate weight-loss membership Membership $39 first month, then $149 monthly |
View provider |
Direct Meds Compounded injections |
$197 promotional Page advertises injections from $197 while its FAQ lists $297/$497 full prices |
$197 promo; $297 listed | $197 promo; $497 listed | Medication, clinician review, supplies and shipping Monthly program; verify current checkout terms |
View provider |
ReflexMD Compounded injections |
$199/mo Page displays promotional and higher standard prices |
$199 promotional | $297 promotional | Prescription review, medication and shipping Promotional pricing; verify current renewal terms |
View provider |
WeightWatchers Med+ FDA-approved Wegovy |
$224 first month $199 starter-dose fill plus $25 first-month membership; later costs rise |
$199 first 2 pen fills | Not on cited page | Wegovy plus separate Med+ membership $74 membership requires a 12-month plan |
View provider |
Prices and provider terms checked August 28, 2026. “Lowest visible total” is not a quality ranking. It may reflect a starter dose, promotion, long-term commitment, or a different medication format.
Read the fine print fast
Three questions catch most pricing surprises.
02
What happens at the next dose?
Some compounded prices rise with dose. Some brand offers cover only the first two starter fills.
03
What must you prepay?
The lowest monthly equivalent may require paying three, six, or twelve months in advance.
Answers before checkout
Common no-insurance questions.
What is the cheapest online GLP-1 without insurance in this comparison?
SurpassMD has the lowest advertised semaglutide starting price among the providers included here at $114 per month. Actual price depends on medication, dose, promotion, and clinical approval, so verify the current offer before purchasing.
Does the monthly price always include medication?
No. Some programs bundle medication, clinical care, shipping, and supplies. Others charge a membership plus the medication. Our table states the basis used for each displayed total.
Are compounded GLP-1 medications FDA-approved?
No. Compounded drugs are not FDA-approved and are not reviewed by the FDA for safety, effectiveness, or quality. A licensed prescriber must decide whether any treatment is appropriate.
Why can prices rise after the first month?
Common reasons include the end of an introductory offer, a higher prescribed dose, a separate membership renewal, or moving from a starter dose to an ongoing dose.
Can I get a prescription just by choosing a provider?
No. Prescription treatment requires an evaluation by a licensed clinician. Eligibility, medication choice, and dose are clinical decisions, and a prescription is not guaranteed.
Shortlist by the cost you will actually pay.
Use the provider directory for source links, pricing dates, and program-by-program caveats.